Developing High-Fidelity Hepatotoxicity Models From Pluripotent Stem Cells

Faithfully recapitulating human physiology “in a dish” from a renewable source remains a holy grail for medicine and pharma. Many procedures have been described that, to a limited extent, exhibit human tissue-specific function in vitro. In particular, incomplete cellular differentiation and/or the l...

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Hlavní autoři: Medine, Claire N., Lucendo-Villarin, Baltasar, Storck, Christopher, Wang, Faye, Szkolnicka, Dagmara, Khan, Ferdous, Pernagallo, Salvatore, Black, James R., Marriage, Howard M., Ross, James A., Bradley, Mark, Iredale, John P., Flint, Oliver, Hay, David C.
Médium: Artigo
Jazyk:Inglês
Vydáno: AlphaMed Press 2013
Témata:
Cell-Based Drug Development, Screening, and Toxicology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697818/
https://ncbi.nlm.nih.gov/pubmed/23757504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2012-0138
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