Sprouty4 correlates with favorable prognosis in perihilar cholangiocarcinoma by blocking the FGFR-ERK signaling pathway and arresting the cell cycle

BACKGROUND: Perihilar cholangiocarcinoma (PHCC) is the most common subtype of cholangiocarcinoma(CCA). We previously investigated the expression pattern of Sprouty(SPRY) in intrahepatic cholangiocarcinoma(ICC), but the expression and clinical significance of SPRY family members in PHCC are still unk...

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Bibliographische Detailangaben
Veröffentlicht in:EBioMedicine
Hauptverfasser: Qiu, Bo, Chen, Tianli, Sun, Rongqi, Liu, Zengli, Zhang, Xiaoming, Li, Zhipeng, Xu, Yunfei, Zhang, Zongli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Research paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921364/
https://ncbi.nlm.nih.gov/pubmed/31761616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.11.021
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