Sprouty4 correlates with favorable prognosis in perihilar cholangiocarcinoma by blocking the FGFR-ERK signaling pathway and arresting the cell cycle

BACKGROUND: Perihilar cholangiocarcinoma (PHCC) is the most common subtype of cholangiocarcinoma(CCA). We previously investigated the expression pattern of Sprouty(SPRY) in intrahepatic cholangiocarcinoma(ICC), but the expression and clinical significance of SPRY family members in PHCC are still unk...

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Udgivet i:EBioMedicine
Main Authors: Qiu, Bo, Chen, Tianli, Sun, Rongqi, Liu, Zengli, Zhang, Xiaoming, Li, Zhipeng, Xu, Yunfei, Zhang, Zongli
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Research paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921364/
https://ncbi.nlm.nih.gov/pubmed/31761616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.11.021
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