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CRF(1) Receptor Signaling via the ERK1/2-MAP and Akt Kinase Cascades: Roles of Src, EGF Receptor, and PI3-Kinase Mechanisms
In the present study, we determined the cellular regulators of ERK1/2 and Akt signaling pathways in response to human CRF(1) receptor (CRF(1)R) activation in transfected COS-7 cells. We found that Pertussis Toxin (PTX) treatment or sequestering Gβγ reduced CRF(1)R-mediated activation of ERK1/2, sugg...
שמור ב:
| הוצא לאור ב: | Front Endocrinol (Lausanne) |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Frontiers Media S.A.
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6921279/ https://ncbi.nlm.nih.gov/pubmed/31920979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00869 |
| תגים: |
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