A newly synthesized platinum-based compound (PBC-II) increases chemosensitivity of HeLa ovarian cancer cells via inhibition of autophagy

There are many mechanisms of resistance, chemoresistance of HeLa cells to anti-cancer agents seems to be autophagy-mediated. While using very effective anti-cancers such as Doxorubicin and cisplatin, cells overcome the cytotoxicity of these drugs through promotion of what so-called cytoprotective au...

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Опубликовано в: :Saudi Pharm J
Главные авторы: Alotaibi, Moureq Rashed, As Sobeai, Homood Moqbel, Alaqil, Faten Abdullah, Almutairi, Mashal, Alhazzani, Khalid, Sulaiman, Adam A.A., Isab, Anvarhusein A., Hadal Alotaibi, Nasser
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6921179/
https://ncbi.nlm.nih.gov/pubmed/31885480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2019.10.003
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