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Sequence dependence of the hyperthermic potentiation of carboplatin-induced cytotoxicity and intracellular platinum accumulation in HeLa cells.

We have examined the enhancement of cytotoxic effects of cis-diammine-1,1-cyclobutane dicarboxylate platinum(II) (carboplatin) by hyperthermia in HeLa cells using different regimes of timing and sequence. The results were compared with those obtained with cis-diamminedichloroplatinum(II) (cisplatin)...

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Autors principals: Kusumoto, T., Maehara, Y., Baba, H., Takahashi, I., Kusumoto, H., Ohno, S., Sugimachi, K.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1968573/
https://ncbi.nlm.nih.gov/pubmed/8347479
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