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Dithiocarbamate as a Valuable Scaffold for the Inhibition of Metallo-β-Lactmases
The ‘superbug’ infection caused by metallo-β-lactamases (MβLs) has grown into an emergent health threat. Given the clinical importance of MβLs, a novel scaffold, dithiocarbamate, was constructed. The obtained molecules, DC1, DC8 and DC10, inhibited MβLs NDM-1, VIM-2, IMP-1, ImiS and L1 from all thre...
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| Publicado no: | Biomolecules |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6920875/ https://ncbi.nlm.nih.gov/pubmed/31694268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9110699 |
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