Design of N-Terminal Derivatives from a Novel Dermaseptin Exhibiting Broad-Spectrum Antimicrobial Activity against Isolates from Cystic Fibrosis Patients

Dermaseptins are an antimicrobial peptide family widely identified from the skin secretions of phyllomeudusinae frogs. Here, we identify Dermaseptin-PC (DM-PC), from the skin secretion of Phyllomedusa coelestis, and further investigate the properties of this peptide, and a number of rationally desig...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Ying, Yuan, Wang, Hui, Xi, Xinping, Ma, Chengbang, Liu, Yue, Zhou, Mei, Du, Qiang, Burrows, James F., Wei, Minjie, Chen, Tianbao, Wang, Lei
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920804/
https://ncbi.nlm.nih.gov/pubmed/31653005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9110646
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