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Broad-Spectrum Antimicrobial Activity and Improved Stability of a D-Amino Acid Enantiomer of DMPC-10A, the Designed Derivative of Dermaseptin Truncates
DMPC-10A (ALWKKLLKK-Cha-NH(2)) is a 10-mer peptide derivative from the N-terminal domain of Dermaseptin-PC which has shown broad-spectrum antimicrobial activity as well as a considerable hemolytic effect. In order to reduce hemolytic activity and improve stability to endogenous enzymes, a D-amino ac...
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| Pubblicato in: | Antibiotics (Basel) |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7557582/ https://ncbi.nlm.nih.gov/pubmed/32967333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics9090627 |
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