Characterisation of transcription factor profiles in polycystic kidney disease (PKD): identification and validation of STAT3 and RUNX1 in the injury/repair response and PKD progression

ABSTRACT: Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic renal disease, caused in the majority of the cases by a mutation in either the PKD1 or the PKD2 gene. ADPKD is characterised by a progressive increase in the number and size of cysts, together with fibrosis and...

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Bibliografiset tiedot
Julkaisussa:J Mol Med (Berl)
Päätekijät: Formica, Chiara, Malas, Tareq, Balog, Judit, Verburg, Lotte, ‘t Hoen, Peter A. C., Peters, Dorien J. M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Berlin Heidelberg 2019
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Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920240/
https://ncbi.nlm.nih.gov/pubmed/31773180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-019-01852-3
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