Reducing YAP expression in Pkd1 mutant mice does not improve the cystic phenotype

The Hippo pathway is a highly conserved signalling route involved in organ size regulation. The final effectors of this pathway are two transcriptional coactivators, yes‐associated protein (YAP) and transcriptional coactivator with PDZ‐binding motif (WWTR1 or TAZ). Previously, we showed aberrant act...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Formica, Chiara, Kunnen, Sandra, Dauwerse, Johannes G., Mullick, Adam E., Dijkstra, Kyra L., Scharpfenecker, Marion, Peters, Dorien J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Short Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7412403/
https://ncbi.nlm.nih.gov/pubmed/32592332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15512
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