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MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors
Cancer is a hyper-proliferative disease. Whether the proliferative state originates from the cell-of-origin or emerges later remains difficult to resolve. By tracking de novo transformation from normal hematopoietic progenitors expressing an acute myeloid leukemia (AML) oncogene MLL-AF9, we reveal t...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6920141/ https://ncbi.nlm.nih.gov/pubmed/31852898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13666-5 |
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