A carregar...
The ribosomal P-stalk couples amino acid starvation to GCN2 activation in mammalian cells
The eukaryotic translation initiation factor 2α (eIF2α) kinase GCN2 is activated by amino acid starvation to elicit a rectifying physiological program known as the Integrated Stress Response (ISR). A role for uncharged tRNAs as activating ligands of yeast GCN2 is supported experimentally. However, m...
Na minha lista:
| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6919976/ https://ncbi.nlm.nih.gov/pubmed/31749445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50149 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|