Microglial activation, but not tau pathology, is independently associated with amyloid positivity and memory impairment

We sought to determine if upstream amyloid accumulation and downstream cognitive impairment have independent relationships with microglial activation and tau pathology. Fifty-eight older adults were stratified by amyloid and cognitive status based on (18)F-florbetaben PET, history, and neuropsycholo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neurobiol Aging
Egile Nagusiak: Zou, James, Tao, Sha, Johnson, Aubrey, Tomljanovic, Zeljko, Polly, Krista, Klein, Julia, Razlighi, Qolamreza R., Brickman, Adam M., Lee, Seonjoo, Stern, Yaakov, Kreisl, William Charles
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6919274/
https://ncbi.nlm.nih.gov/pubmed/31698286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.09.019
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