Microglial activation, but not tau pathology, is independently associated with amyloid positivity and memory impairment

We sought to determine if upstream amyloid accumulation and downstream cognitive impairment have independent relationships with microglial activation and tau pathology. Fifty-eight older adults were stratified by amyloid and cognitive status based on (18)F-florbetaben PET, history, and neuropsycholo...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Zou, James, Tao, Sha, Johnson, Aubrey, Tomljanovic, Zeljko, Polly, Krista, Klein, Julia, Razlighi, Qolamreza R., Brickman, Adam M., Lee, Seonjoo, Stern, Yaakov, Kreisl, William Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6919274/
https://ncbi.nlm.nih.gov/pubmed/31698286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2019.09.019
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