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An averaging strategy to reduce variability in target-decoy estimates of false discovery rate

Decoy database search with target-decoy competition (TDC) provides an intuitive, easy-to-implement method for estimating the false discovery rate (FDR) associated with spectrum identifications from shotgun proteomics data. However, the procedure can yield different results for a fixed dataset analyz...

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Bibliografische gegevens
Gepubliceerd in:J Proteome Res
Hoofdauteurs: Keich, Uri, Tamura, Kaipo, Noble, William Stafford
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6919216/
https://ncbi.nlm.nih.gov/pubmed/30560673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.8b00802
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