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Rnd Proteins Function as RhoA Antagonists by Activating p190 RhoGAP

BACKGROUND: The Rnd proteins Rnd1, Rnd2, and Rnd3(RhoE) comprise a unique branch of Rho-family G-proteins that lack intrinsic GTPase activity, and consequently remain constitutively “active”. Prior studies have suggested that Rnd proteins play pivotal roles in cell regulation by counteracting the bi...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Biol
Hauptverfasser: Wennerberg, Krister, Forget, Marie-Annick, Ellerbroek, Shawn M., Arthur, William T., Burridge, Keith, Settleman, Jeffrey, Der, Channing J., Hansen, Steen H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918695/
https://ncbi.nlm.nih.gov/pubmed/12842009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/s0960-9822(03)00418-4
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