Evaluation of gene-environment interactions for colorectal cancer susceptibility loci using case-only and case-control designs

BACKGROUND: Genome-wide association studies (GWAS) have identified more than 40 colorectal cancer susceptibility loci, but only a small fraction of heritability was explained. To account for missing heritability, we investigated gene-environment interactions (G × Es) between GWAS-identified single-n...

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Udgivet i:BMC Cancer
Main Authors: Song, Nan, Lee, Jeeyoo, Cho, Sooyoung, Kim, Jeongseon, Oh, Jae Hwan, Shin, Aesun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918639/
https://ncbi.nlm.nih.gov/pubmed/31849324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6456-9
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