Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice

BACKGROUND: Alzheimer disease (AD) is characterized by the accumulation of beta-amyloid (Aβ) plaques and neurofibrillary tangles composed of hyperphosphorylated tau, which together lead to neurodegeneration and cognitive decline. Current therapeutic approaches have primarily aimed to reduce patholog...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Alzheimers Res Ther
Κύριοι συγγραφείς: Davtyan, Hayk, Hovakimyan, Armine, Kiani Shabestari, Sepideh, Antonyan, Tatevik, Coburn, Morgan A., Zagorski, Karen, Chailyan, Gor, Petrushina, Irina, Svystun, Olga, Danhash, Emma, Petrovsky, Nikolai, Cribbs, David H., Agadjanyan, Michael G., Blurton-Jones, Mathew, Ghochikyan, Anahit
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2019
Θέματα:
Research
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918571/
https://ncbi.nlm.nih.gov/pubmed/31847886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0556-2
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