Capacity to Elicit Cytotoxic CD8 T Cell Activity Against Mycobacterium avium subsp. paratuberculosis Is Retained in a Vaccine Candidate 35 kDa Peptide Modified for Expression in Mammalian Cells

Studies focused on development of an attenuated vaccine against Mycobacterium avium subsp. paratuberculosis (Map), the causative agent of paratuberculosis (Ptb) in cattle and other species, revealed that deletion of relA, a global gene regulator, abrogates the ability of Map to establish a persisten...

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Publicado en:Front Immunol
Main Authors: Franceschi, Valentina, Mahmoud, Asmaa H., Abdellrazeq, Gaber S., Tebaldi, Giulia, Macchi, Francesca, Russo, Luca, Fry, Lindsay M., Elnaggar, Mahmoud M., Bannantine, John P., Park, Kun-Taek, Hulubei, Victoria, Cavirani, Sandro, Davis, William C., Donofrio, Gaetano
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917596/
https://ncbi.nlm.nih.gov/pubmed/31921129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02859
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