Evaluation of two mutants of Mycobacterium avium subsp. paratuberculosis as candidates for a live attenuated vaccine for Johne’s disease

Control of Johne’s disease, caused by Mycobacterium avium subsp. paratuberculosis, has been difficult because of a lack of an effective vaccine. To address this problem we used targeted gene disruption to develop candidate mutants with impaired capacity to survive ex vivo and in vivo to test as a va...

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Главные авторы: Park, Kun Taek, Allen, Andrew J., Bannantine, John P., Seo, Keun Seok, Hamilton, Mary J., Abdellrazeq, Gaber S., Rihan, Heba M., Grimm, Amanda, Davis, William C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114198/
https://ncbi.nlm.nih.gov/pubmed/21565243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.04.090
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