Capacity to Elicit Cytotoxic CD8 T Cell Activity Against Mycobacterium avium subsp. paratuberculosis Is Retained in a Vaccine Candidate 35 kDa Peptide Modified for Expression in Mammalian Cells

Studies focused on development of an attenuated vaccine against Mycobacterium avium subsp. paratuberculosis (Map), the causative agent of paratuberculosis (Ptb) in cattle and other species, revealed that deletion of relA, a global gene regulator, abrogates the ability of Map to establish a persisten...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Franceschi, Valentina, Mahmoud, Asmaa H., Abdellrazeq, Gaber S., Tebaldi, Giulia, Macchi, Francesca, Russo, Luca, Fry, Lindsay M., Elnaggar, Mahmoud M., Bannantine, John P., Park, Kun-Taek, Hulubei, Victoria, Cavirani, Sandro, Davis, William C., Donofrio, Gaetano
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917596/
https://ncbi.nlm.nih.gov/pubmed/31921129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02859
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