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Combined use of CSF NfL and CSF TDP‐43 improves diagnostic performance in ALS

OBJECTIVE: To determine the diagnostic and prognostic significance of neurofilament light chain (NfL), TAR DNA‐binding protein 43 (TDP‐43), and total tau (t‐tau) in cerebrospinal fluid (CSF) and plasma of patients with amyotrophic lateral sclerosis (ALS) and to investigate whether the combined use o...

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Detalles Bibliográficos
Publicado en:Ann Clin Transl Neurol
Autores principales: Kasai, Takashi, Kojima, Yuta, Ohmichi, Takuma, Tatebe, Harutsugu, Tsuji, Yukiko, Noto, Yu‐ichi, Kitani‐Morii, Fukiko, Shinomoto, Makiko, Allsop, David, Mizuno, Toshiki, Tokuda, Takahiko
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917342/
https://ncbi.nlm.nih.gov/pubmed/31742901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.50943
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