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Combined use of CSF NfL and CSF TDP‐43 improves diagnostic performance in ALS

OBJECTIVE: To determine the diagnostic and prognostic significance of neurofilament light chain (NfL), TAR DNA‐binding protein 43 (TDP‐43), and total tau (t‐tau) in cerebrospinal fluid (CSF) and plasma of patients with amyotrophic lateral sclerosis (ALS) and to investigate whether the combined use o...

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Bibliografiske detaljer
Udgivet i:Ann Clin Transl Neurol
Main Authors: Kasai, Takashi, Kojima, Yuta, Ohmichi, Takuma, Tatebe, Harutsugu, Tsuji, Yukiko, Noto, Yu‐ichi, Kitani‐Morii, Fukiko, Shinomoto, Makiko, Allsop, David, Mizuno, Toshiki, Tokuda, Takahiko
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6917342/
https://ncbi.nlm.nih.gov/pubmed/31742901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.50943
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