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Biomarker repurposing: Therapeutic drug monitoring of serum theophylline offers a potential diagnostic biomarker of Parkinson’s disease

Caffeine has been considered a neuroprotective agent against Parkinson’s disease (PD). Recent metabolomic analysis showed that levels of caffeine and its metabolites were decreased in sera from patients with PD compared with those from healthy controls. We focused on theophylline, which is one of th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ohmichi, Takuma, Kasai, Takashi, Kosaka, Tadashi, Shikata, Keisuke, Tatebe, Harutsugu, Ishii, Ryotaro, Shinomoto, Makiko, Mizuno, Toshiki, Tokuda, Takahiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6059449/
https://ncbi.nlm.nih.gov/pubmed/30044870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201260
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