Plasma neurofilament light chain: A potential prognostic biomarker of dementia in adult Down syndrome patients

People with Down syndrome (DS) are at high risk of developing Alzheimer disease (AD) with aging. The diagnosis and treatment trials are hampered by a lack of reliable blood biomarkers. Plasma neurofilament light chain (NfL) is one of the established biomarkers of AD, suggesting that it may be useful...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shinomoto, Makiko, Kasai, Takashi, Tatebe, Harutsugu, Kondo, Masaki, Ohmichi, Takuma, Morimoto, Masafumi, Chiyonobu, Tomohiro, Terada, Naoto, Allsop, David, Yokota, Isao, Mizuno, Toshiki, Tokuda, Takahiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450630/
https://ncbi.nlm.nih.gov/pubmed/30951523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211575
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