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Children with Narcolepsy type 1 have increased T‐cell responses to orexins
Narcolepsy type 1 (NT1) is caused by severe loss of the orexin neurons, and is highly associated with HLA DQB1*06:02. Using intracellular cytokine staining, we observed a higher frequency of IFN‐γ‐ and TNF‐α‐producing CD4(+) and CD8(+) T‐cells in response to orexins in 27 children with NT1 compared...
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| Izdano u: | Ann Clin Transl Neurol |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6917326/ https://ncbi.nlm.nih.gov/pubmed/31730293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.50908 |
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