Concomitant loss of dynorphin, NARP, and orexin in narcolepsy

BACKGROUND: Narcolepsy with cataplexy is associated with a loss of orexin/hypocretin. It is speculated that an autoimmune process kills the orexin-producing neurons, but these cells may survive yet fail to produce orexin. OBJECTIVE: To examine whether other markers of the orexin neurons are lost in...

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Bibliografiske detaljer
Main Authors: Crocker, Amanda, España, Rodrigo A., Papadopoulou, Maria, Saper, Clifford B., Faraco, Juliette, Sakurai, Takeshi, Honda, Makoto, Mignot, Emmanuel, Scammell, Thomas E.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2254145/
https://ncbi.nlm.nih.gov/pubmed/16247044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/01.wnl.0000168173.71940.ab
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