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Dual orexin receptor antagonists increase sleep and cataplexy in wild type mice
Orexin receptor antagonists are clinically useful for treating insomnia, but thorough blockade of orexin signaling could cause narcolepsy-like symptoms. Specifically, while sleepiness is a desirable effect, an orexin antagonist could also produce cataplexy, sudden episodes of muscle weakness often t...
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| Publicado en: | Sleep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7294412/ https://ncbi.nlm.nih.gov/pubmed/31830270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/sleep/zsz302 |
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