Abnormal Sleep/Wake Dynamics in Orexin Knockout Mice

STUDY OBJECTIVES: Narcolepsy with cataplexy is caused by a loss of orexin (hypocretin) signaling, but the physiologic mechanisms that result in poor maintenance of wakefulness and fragmented sleep remain unknown. Conventional scoring of sleep cannot reveal much about the process of transitioning bet...

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Bibliografische gegevens
Hoofdauteurs: Diniz Behn, Cecilia G., Klerman, Elizabeth B., Mochizuki, Takatoshi, Lin, Shih-Chieh, Scammell, Thomas E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Associated Professional Sleep Societies, LLC 2010
Onderwerpen:
Sleep/Wake Dynamics in Orexin Knockout Mice
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831423/
https://ncbi.nlm.nih.gov/pubmed/20337187
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