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In Vitro Pluripotent Stem Cell Differentiation to Hepatocyte Ceases Further Maturation at an Equivalent Stage of E15 in Mouse Embryonic Liver Development

Hepatocyte-like cells (HLCs) can be derived from pluripotent stem cells (PSCs) by sequential treatment of chemical cues to mimic the microenvironment of embryonic liver development. However, these HLCs do not reach the full maturity level of primary hepatocytes. In this study, we carried out a meta-...

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Bibliografski detalji
Izdano u:Stem Cells Dev
Glavni autori: Raju, Ravali, Chau, David, Notelaers, Tineke, Myers, Chad L., Verfaillie, Catherine M., Hu, Wei-Shou
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916117/
https://ncbi.nlm.nih.gov/pubmed/29851366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2017.0270
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