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Culture of Mouse Embryonic Stem Cells with Serum but without Exogenous Growth Factors Is Sufficient to Generate Functional Hepatocyte-Like Cells

Mouse embryonic stem cells (mESC) have been used to study lineage specification in vitro, including towards a hepatocyte-like fate, and such investigations guided lineage differentiation protocols for human (h)ESC. We recently described a four-step protocol to induce hepatocyte-like cells from hESC...

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Detalhes bibliográficos
Main Authors: Pauwelyn, Karen, Roelandt, Philip, Notelaers, Tineke, Sancho-Bru, Pau, Fevery, Johan, Verfaillie, Catherine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149071/
https://ncbi.nlm.nih.gov/pubmed/21829697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023096
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