Human Embryonic and Rat Adult Stem Cells with Primitive Endoderm-Like Phenotype Can Be Fated to Definitive Endoderm, and Finally Hepatocyte-Like Cells

Stem cell-derived hepatocytes may be an alternative cell source to treat liver diseases or to be used for pharmacological purposes. We developed a protocol that mimics mammalian liver development, to differentiate cells with pluripotent characteristics to hepatocyte-like cells. The protocol supports...

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Autors principals: Roelandt, Philip, Pauwelyn, Karen Ann, Sancho-Bru, Pau, Subramanian, Kartik, Bose, Bipasha, Ordovas, Laura, Vanuytsel, Kim, Geraerts, Martine, Firpo, Meri, De Vos, Rita, Fevery, Johan, Nevens, Frederik, Hu, Wei-Shou, Verfaillie, Catherine M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920330/
https://ncbi.nlm.nih.gov/pubmed/20711405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012101
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