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Spheroid Culture for Enhanced Differentiation of Human Embryonic Stem Cells to Hepatocyte-Like Cells

Stem cell-derived hepatocyte-like cells hold great potential for the treatment of liver disease and for drug toxicity screening. The success of these applications hinges on the generation of differentiated cells with high liver specific activities. Many protocols have been developed to guide human e...

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Autors principals: Subramanian, Kartik, Owens, Derek Jason, Raju, Ravali, Firpo, Meri, O'Brien, Timothy D., Verfaillie, Catherine M., Hu, Wei-Shou
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887452/
https://ncbi.nlm.nih.gov/pubmed/24020366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2013.0097
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