Ubiquitin-specific protease 22 is critical to in vivo angiogenesis, growth and metastasis of non-small cell lung cancer

BACKGROUND: Loss of monoubiquitination of histone H2B (H2Bub1) was found to be associated with poor differentiation, cancer stemness, and enhanced malignancy of non-small cell lung cancer (NSCLC). Herein, we investigated the biological significance and therapeutic implications of ubiquitin-specific...

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Dettagli Bibliografici
Pubblicato in:Cell Commun Signal
Autori principali: Zhang, Keqiang, Yang, Lu, Wang, Jinhui, Sun, Ting, Guo, Yuming, Nelson, Rebecca, Tong, Tommy R., Pangeni, Rajendra, Salgia, Ravi, Raz, Dan J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916027/
https://ncbi.nlm.nih.gov/pubmed/31842906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0480-x
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