Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice

Activated Caspase-6 (Casp6) is associated with age-dependent cognitive impairment and Alzheimer disease (AD). Mice expressing human Caspase-6 in hippocampal CA1 neurons develop age-dependent cognitive deficits, neurodegeneration and neuroinflammation. This study assessed if methylene blue (MB), a ph...

全面介紹

Na minha lista:
書目詳細資料
發表在:Acta Neuropathol Commun
Main Authors: Zhou, Libin, Flores, Joseph, Noël, Anastasia, Beauchet, Olivier, Sjöström, P. Jesper, LeBlanc, Andrea C.
格式: Artigo
語言:Inglês
出版: BioMed Central 2019
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915996/
https://ncbi.nlm.nih.gov/pubmed/31843022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0856-6
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍