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Differential susceptibility of striatal, hippocampal and cortical neurons to Caspase-6

Active cysteinyl protease Caspase-6 is associated with early Alzheimer and Huntington diseases. Higher entorhinal cortex and hippocampal Caspase-6 levels correlate with lower cognitive performance in aged humans. Caspase-6 induces axonal degeneration in human primary neuron cultures and causes infla...

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Détails bibliographiques
Publié dans:Cell Death Differ
Auteurs principaux: Noël, Anastasia, Zhou, Libin, Foveau, Bénédicte, Sjöström, P. Jesper, LeBlanc, Andréa C.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030053/
https://ncbi.nlm.nih.gov/pubmed/29352267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0043-x
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