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Modification of Aβ Peptide Aggregation via Covalent Binding of a Series of Ru(III) Complexes

Alzheimer's disease (AD) is the most common form of dementia, leading to loss of cognition, and eventually death. The disease is characterized by the formation of extracellular aggregates of the amyloid-beta (Aβ) peptide and neurofibrillary tangles of tau protein inside cells, and oxidative str...

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Bibliografiske detaljer
Udgivet i:Front Chem
Main Authors: Gomes, Luiza M. F., Bataglioli, Janaina C., Jussila, Allison J., Smith, Jason R., Walsby, Charles J., Storr, Tim
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915085/
https://ncbi.nlm.nih.gov/pubmed/31921764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00838
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