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Modification of Aβ Peptide Aggregation via Covalent Binding of a Series of Ru(III) Complexes

Alzheimer's disease (AD) is the most common form of dementia, leading to loss of cognition, and eventually death. The disease is characterized by the formation of extracellular aggregates of the amyloid-beta (Aβ) peptide and neurofibrillary tangles of tau protein inside cells, and oxidative str...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Gomes, Luiza M. F., Bataglioli, Janaina C., Jussila, Allison J., Smith, Jason R., Walsby, Charles J., Storr, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6915085/
https://ncbi.nlm.nih.gov/pubmed/31921764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00838
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