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A catalytic antioxidant for limiting amyloid-beta peptide aggregation and reactive oxygen species generation
Alzheimer's disease (AD) is a multifaceted disease that is characterized by increased oxidative stress, metal-ion dysregulation, and the formation of intracellular neurofibrillary tangles and extracellular amyloid-β (Aβ) aggregates. In this work we report the large affinity binding of the iron(...
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| Udgivet i: | Chem Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Royal Society of Chemistry
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6369440/ https://ncbi.nlm.nih.gov/pubmed/30842826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04660c |
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