A catalytic antioxidant for limiting amyloid-beta peptide aggregation and reactive oxygen species generation

Alzheimer's disease (AD) is a multifaceted disease that is characterized by increased oxidative stress, metal-ion dysregulation, and the formation of intracellular neurofibrillary tangles and extracellular amyloid-β (Aβ) aggregates. In this work we report the large affinity binding of the iron(...

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Detaylı Bibliyografya
Yayımlandı:Chem Sci
Asıl Yazarlar: Gomes, Luiza M. F., Mahammed, Atif, Prosser, Kathleen E., Smith, Jason R., Silverman, Michael A., Walsby, Charles J., Gross, Zeev, Storr, Tim
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Royal Society of Chemistry 2018
Konular:
Chemistry
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369440/
https://ncbi.nlm.nih.gov/pubmed/30842826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04660c
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