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Structural basis for a species-specific determinant of an SIV Vif protein towards hominid APOBEC3G antagonism
Primate lentiviruses encode a Vif protein that counteracts the host antiviral APOBEC3 (A3) family members. The adaptation of Vif to species-specific A3 determinants is a critical event that allowed the spillover of a lentivirus from monkey reservoirs to chimpanzees and subsequently to humans, which...
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| Udgivet i: | Cell Host Microbe |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6913891/ https://ncbi.nlm.nih.gov/pubmed/31830442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.10.014 |
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