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Structural basis for a species-specific determinant of an SIV Vif protein towards hominid APOBEC3G antagonism

Primate lentiviruses encode a Vif protein that counteracts the host antiviral APOBEC3 (A3) family members. The adaptation of Vif to species-specific A3 determinants is a critical event that allowed the spillover of a lentivirus from monkey reservoirs to chimpanzees and subsequently to humans, which...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Binning, Jennifer M., Chesarino, Nicholas M., Emerman, Michael, Gross, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913891/
https://ncbi.nlm.nih.gov/pubmed/31830442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.10.014
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