Načítá se...

A uniparental isodisomy event introducing homozygous pathogenic variants drives a multisystem metabolic disorder

Uniparental isodisomy (UPiD) is a rare genetic event that occurs when two identical copies of a single chromosome are inherited from one parent. Here we report a patient with a severe, multisystem metabolic disorder who inherited two copies of Chromosome 12 from her father. He was a heterozygous car...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Cold Spring Harb Mol Case Stud
Hlavní autoři: Daniels, Eileen G., Alders, Marielle, Lezzerini, Marco, McDonald, Andrew, Peters, Marjolein, Kuijpers, Taco W., Lakeman, Phillis, Houtkooper, Riekelt H., MacInnes, Alyson W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913148/
https://ncbi.nlm.nih.gov/pubmed/31653659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a004457
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!