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Direct RNA sequencing enables m(6)A detection in endogenous transcript isoforms at base-specific resolution
Direct RNA sequencing holds great promise for the de novo identification of RNA modifications at single-coordinate resolution; however, interpretation of raw sequencing output to discover modified bases remains a challenge. Using Oxford Nanopore's direct RNA sequencing technology, we developed...
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| Veröffentlicht in: | RNA |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6913132/ https://ncbi.nlm.nih.gov/pubmed/31624092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.072785.119 |
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