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Explicit DNase sequence bias modeling enables high-resolution transcription factor footprint detection

DNaseI footprinting is an established assay for identifying transcription factor (TF)–DNA interactions with single base pair resolution. High-throughput DNase-seq assays have recently been used to detect in vivo DNase footprints across the genome. Multiple computational approaches have been develope...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Yardımcı, Galip Gürkan, Frank, Christopher L., Crawford, Gregory E., Ohler, Uwe
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231734/
https://ncbi.nlm.nih.gov/pubmed/25294828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku810
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