Intradermal HIV-1 DNA Immunization Using Needle-Free Zetajet Injection Followed by HIV-Modified Vaccinia Virus Ankara Vaccination Is Safe and Immunogenic in Mozambican Young Adults: A Phase I Randomized Controlled Trial

We assessed the safety and immunogenicity of HIV-DNA priming using Zetajet™, a needle-free device intradermally followed by intramuscular HIV-MVA boosts, in 24 healthy Mozambicans. Volunteers were randomized to receive three immunizations of 600 μg (n = 10; 2 × 0.1 ml) or 1,200 μg (n = 10; 2 × 0.2 m...

詳細記述

保存先:
書誌詳細
出版年:AIDS Res Hum Retroviruses
主要な著者: Viegas, Edna Omar, Tembe, Nelson, Nilsson, Charlotta, Meggi, Bindiya, Maueia, Cremildo, Augusto, Orvalho, Stout, Richard, Scarlatti, Gabriella, Ferrari, Guido, Earl, Patricia L., Wahren, Britta, Andersson, Sören, Robb, Merlin L., Osman, Nafissa, Biberfeld, Gunnel, Jani, Ilesh, Sandström, Eric
フォーマット: Artigo
言語:Inglês
出版事項: Mary Ann Liebert, Inc. 2018
主題:
Vaccines
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913121/
https://ncbi.nlm.nih.gov/pubmed/28969431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2017.0121
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