HIV-DNA Given with or without Intradermal Electroporation Is Safe and Highly Immunogenic in Healthy Swedish HIV-1 DNA/MVA Vaccinees: A Phase I Randomized Trial

BACKGROUND: We compared safety and immunogenicity of intradermal (ID) vaccination with and without electroporation (EP) in a phase I randomized placebo-controlled trial of an HIV-DNA prime HIV-MVA boost vaccine in healthy Swedish volunteers. METHODS: HIV-DNA plasmids encoding HIV-1 genes gp160 subty...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nilsson, Charlotta, Hejdeman, Bo, Godoy-Ramirez, Karina, Tecleab, Teghesti, Scarlatti, Gabriella, Bråve, Andreas, Earl, Patricia L., Stout, Richard R., Robb, Merlin L., Shattock, Robin J., Biberfeld, Gunnel, Sandström, Eric, Wahren, Britta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486388/
https://ncbi.nlm.nih.gov/pubmed/26121679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131748
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