Recombinant Modified Vaccinia Ankara (MVA) effectively boosts DNA-primed HIV-specific immune responses in humans despite pre-existing vaccinia immunity

The presence of vector-specific immune responses may hamper the induction of responses to a foreign antigen encoded by the vector. We evaluated the impact of pre-existing immunity to vaccinia virus on the induction of HIV-specific responses after immunization of healthy volunteers with a HIV-1 DNA p...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Gudmundsdotter, Lindvi, Nilsson, Charlotta, Brave, Andreas, Hejdeman, Bo, Earl, Patricia, Moss, Bernard, Robb, Merlin, Cox, Josephine, Michael, Nelson, Marovich, Mary, Biberfeld, Gunnel, Sandström, Eric, Wahren, Britta
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788966/
https://ncbi.nlm.nih.gov/pubmed/19450644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.05.018
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