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Reducing Th2 inflammation through neutralizing IL-4 antibody rescues myelination in IUGR rat brain

BACKGROUND: Intrauterine growth restriction (IUGR) is a common complication of pregnancy and is associated with significant neurological deficits in infants, including white matter damage. Previous work using an animal model of IUGR has demonstrated that IUGR rats exhibit neurobehavioral deficits an...

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Bibliografiska uppgifter
I publikationen:J Neurodev Disord
Huvudupphovsmän: Zanno, Allison E., Romer, Micah A., Fox, Lauren, Golden, Thea, Jaeckle-Santos, Lane, Simmons, Rebecca A., Grinspan, Judith B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913005/
https://ncbi.nlm.nih.gov/pubmed/31839002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11689-019-9297-6
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