Neutralizing Th2 Inflammation in Neonatal Islets Prevents β-Cell Failure in Adult IUGR Rats

Intrauterine growth restriction (IUGR) leads to development of type 2 diabetes (T2D) in adulthood. The mechanisms underlying this phenomenon have not been fully elucidated. Inflammation is associated with T2D; however, it is unknown whether inflammation is causal or secondary to the altered metaboli...

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Main Authors: Jaeckle Santos, Lane J., Li, Changhong, Doulias, Paschalis-Thomas, Ischiropoulos, Harry, Worthen, G. Scott, Simmons, Rebecca A.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2014
Teme:
Islet Studies
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994952/
https://ncbi.nlm.nih.gov/pubmed/24408314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1226
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